Hi, Persia 

Firstly, I would like to sincerely apologize for the delayed response as we have been experiencing an unusually high number of tickets. I am sorry that it has taken longer than usual to respond to your concern and your patience is highly appreciated.

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We currently don't have any native a built-in integration with a plugin such as ACF , or Metabox .

Pulling the data from that plugin into wpDataTables,

or generally pulling  data from Custom Post Types would have to be done with MySQL query-based tables.

You can make JOINS between tables in custom SQL Queries, to load data from multiple tables.

Please note: Using this plugin feature requires at least a basic knowledge of SQL. It is assumed that you can create the table in some MySQL data manager (e.g., PHPMyAdmin, MySQL Workbench), and prepare a SQL query that will return the data you need. 

Please be advised that preparing MySQL queries for you is not included in the plugin support.

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As the custom posts/fields, are a part of the WordPress database;

a good way to achieve this can be experimenting using our WPDB SQL Query Constructor tool.

- Please note: this tool is not an ultimate query generator. It simply constructs a suggestion of a query. We are constantly working to improve it, but SQL is such a complicated and flexible language that full automation for constructing queries is next to impossible. 

Consequently, the more complicated the query, the higher is the probability that it will not return exactly what you need. So, you will often need to play around with the resulting query.